9700/12 Biology Oct Nov 2011 Online Test | Cambridge AS and A Level MCQ
The sequence of bases in mRNA for the first eight amino acids in the β-polypeptide of adult haemoglobin is:
GUG–CAC–CUG–ACU–CCU–GAG–GAG–AAG.
In haemoglobin C, which is a cause of haemolytic anaemia, the sequence is:
GUG–CAC–CUG–ACU–CCU–AAG–GAG–AAG.
The coding for seven of the amino acids is listed.
Which change occurs to the amino acid sequence of adult haemoglobin to make haemoglobin C?