The drug ritonavir is sometimes used in the treatment of HIV / AIDS.
Ritonavir consists of three amino acids and is a competitive inhibitor of HIV protease. HIV causes
this protease to be made inside human cells.
Ritonavir produces many side effects as it interferes with many metabolic processes in human
cells.
Which statements about ritonavir are correct?
1) Ritonavir has a shape complementary to the active site of HIV protease.
2) Ritonavir will enter human cells directly through the lipid bilayer and not require any transport proteins.
3) Ritonavir is likely to inhibit many of the enzymes of human cells.
4) Complete hydrolysis of ritonavir would require the addition of three water molecules.
1 )
1, 2 and 3
1 and 3 only
3 )
2 and 4
4 )
3 and 4
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