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The graph shows the effect of substrate concentration on the initial rate of an enzyme-catalysed reaction. The enzyme concentration is constant.

Which statement about the graph is correct?

1 ) 

Between R and S the number of enzyme molecules is limiting the rate of reaction.

2 ) 

Between R and S the number of product molecules is limiting the rate of reaction.

3 ) 

Between S and T the number of enzyme molecules is limiting the rate of reaction.

4 ) 

Between S and T the number of substrate molecules is limiting the rate of reaction.

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