The enzymes glucokinase in the liver and hexokinase in the brain both catalyse the phosphorylation of glucose:
glucose + ATP $ \to $ glucose phosphate + ADP
The activity of each enzyme was measured at different concentrations of glucose. The graph shows the results.
What describes the different activities of the two enzymes?
1 )
Both enzymes hold glucose and ATP molecules together at the active site.
2 )
Glucokinase becomes saturated with glucose at a lower concentration of glucose than hexokinase.
3 )
Glucokinase phosphorylates more molecules of glucose per minute.
The affinity of hexokinase for glucose is greater than that of glucokinase.
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