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The enzymes glucokinase in the liver and hexokinase in the brain both catalyse the phosphorylation of glucose:  

glucose + ATP $ \to $ glucose phosphate + ADP 

The activity of each enzyme was measured at different concentrations of glucose. The graph shows the results. 

What describes the different activities of the two enzymes?

1 ) 

Both enzymes hold glucose and ATP molecules together at the active site. 

2 ) 

Glucokinase becomes saturated with glucose at a lower concentration of glucose than hexokinase.  

3 ) 

Glucokinase phosphorylates more molecules of glucose per minute. 

4 ) 

The affinity of hexokinase for glucose is greater than that of glucokinase. 

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