In what order do the following processes occur to produce a population of bacteria that are resistant to a new antibiotic?
1 change in reproductive success of bacteria
2 increase in frequency of the resistance allele in the population
3 increase in genetic variation within the population
4 random mutation occurs in bacterial DNA
1 )
$1 \to 3 \to 2 \to 4$
2 )
$2 \to 1 \to 3 \to 4$
3 )
$3 \to 4 \to 1 \to 2$
$4 \to 3 \to 1 \to 2$
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