A patient with kidney failure can be given a kidney transplant. In a kidney transplant, a healthy kidney is taken from another person and put into the patient’s body.
Sometimes the donated kidney cells are killed by the patient’s body. In this primary immune response, T-lymphocytes bind to antigens on the donated kidney cells and are activated.
The statements describe the next stages of the primary immune response.
1- Activated T-lymphocyte secretes cytokines.
2- B-lymphocytes differentiate into plasma cells and make antibodies.
3- T-killer cells bind to antigens on donor kidney cells.
4- T-killer cells release toxins that destroy the donor kidney cells.
5- T-lymphocytes multiply by mitosis and differentiate into T-killer cells.
Which order correctly explains how donor kidney cells are killed?
1 )
$1 \to 5 \to 2 \to 3$
$1 \to 5 \to 3 \to 4$
3 )
$3 \to 1 \to 5 \to 2$
4 )
$3 \to 5 \to 4 \to 1$
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