Some animals produce antimicrobial proteins which protect them from pathogens. These proteins could be used to kill human pathogens, however when used as a medicine they are broken down by protein-digesting enzymes.
Replacing one of the amino acids found in the protein with one that had been synthesised in the laboratory resulted in a modified protein that was not broken down.
What could explain why this modified protein was not broken down by the protein digesting enzymes?
1 The modified protein has a different tertiary structure to the original protein.
2 The modified protein is not complementary in shape to the enzyme’s active site.
3 The modified protein is unable to induce a fit with the protein digesting enzyme.
1, 2 and 3
2 )
1 and 2 only
3 )
2 and 3 only
4 )
2 only
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