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Monoclonal antibodies are used to test for the presence of the hormone HCG in the urine of a human female during early pregnancy.

Which statements describe how the monoclonal antibodies used in this test are produced?

1 HCG is injected into a mouse, and plasma cells in the mouse produce antibodies specific to HCG.

2 Antibodies are extracted from the mouse and then fused with cancer cells to produce hybridoma cells.

3 Single hybridoma cells are cultured and they divide by mitosis to produce a clone of hybridoma cells. 

1 ) 

1, 2 and 3

2 ) 

1 and 2 only

3 ) 

1 and 3 only

4 ) 

2 and 3 only

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