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Comorbidity is where an individual has two or more diseases or medical conditions at the same time. Some medical conditions are particularly likely to result in comorbidity. In one example, initial infection with one pathogen can increase the risk of developing a second disease by a factor of 15 or more. The second disease is then the major cause of death for these people.

Which description could fit this example?

1 ) 

cholera infection followed by development of malaria

2 ) 

cholera infection followed by development of AIDS

3 ) 

HIV infection followed by development of TB

4 ) 

malaria infection followed by development of TB

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