Rheumatoid arthritis is a disease which causes the body’s immune system to attack its own cells. The disease can be treated using monoclonal antibodies.
The table shows how five different monoclonal antibodies can work.
Inflammation and swelling of joints are symptoms of rheumatoid arthritis. The cytokine, TNFalpha, activates cells in the immune system leading to death of cells in the joint.
Which types of monoclonal antibody could be used to treat rheumatoid arthritis?

1 )
1, 2, 3, 4 and 5
2 )
1, 2, 3 and 4 only
3 )
2, 3 and 5 only
4 and 5 only
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