Scientists have made a nucleic acid, HNA, that has a sugar with the same number of carbon atoms as glucose instead of deoxyribose. Although genetic information can be stored by HNA, naturally occurring DNA polymerase cannot replicate HNA.
Which statements could explain why naturally occurring DNA polymerase cannot replicate HNA?
1 DNA polymerase cannot form bonds between the sugars of two HNA nucleotides.
2 DNA polymerase cannot form hydrogen bonds between two HNA nucleotides.
3 HNA nucleotides do not fit into the active site of DNA polymerase.
4 The shape of an HNA nucleotide is slightly larger than that of a DNA nucleotide.
1 )
1, 2, 3 and 4
2 )
1 and 4 only
3 )
2 and 3 only
3 and 4 only
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