The graph shows two oxygen dissociation curves, one for a tissue at rest and one for the same tissue during exercise.
What factors have caused the difference in the position of the dissociation curve during exercise compared with the dissociation curve for the tissue at rest?
1) increase in pH
2) decrease in pH
3) increase in haemoglobin affinity for ${O_2}$
4) decrease in haemoglobin affinity for ${O_2}$
1 )
1 and 3
2 )
1 and 4
3 )
2 and 3
2 and 4
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