Which statement is correct about how oxygen combines with haemoglobin?
1 )
Combining all four oxygen molecules with haemoglobin does not affect the shape of haemoglobin.
One oxygen molecule can combine with each haem group of the haemoglobin molecule.
3 )
The first oxygen molecule to combine with haemoglobin does not affect the shape of haemoglobin.
4 )
The third oxygen molecule to combine with haemoglobin makes it more difficult for the fourth oxygen molecule to combine with haemoglobin.
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