Which statement about the Michaelis–Menten constant (${K_m}$) is correct for an enzyme with a low affinity for its substrate?
It has a high ${K_m}$ and reaches ${V_{\max }}$ at a high substrate concentration.
2 )
It has a high ${K_m}$ and reaches ${V_{\max }}$ at a low substrate concentration.
3 )
It has a low ${K_m}$ and reaches ${V_{\max }}$ at a high substrate concentration.
4 )
It has a low ${K_m}$ and reaches ${V_{\max }}$ at a low substrate concentration.
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