The sequence of bases in DNA coding for the first eight amino acids in the $\beta $-polypeptide of adult haemoglobin is:
CAC GTG GAC TGA GGA CTC CTC TTC
However, in haemoglobin C, which is a cause of haemolytic anaemia, it becomes:
CAC GTG GAC TGA GGA TTC CTC TTC
Some of the DNA triplets that code for the amino acids are listed in the table.
Which change occurs to the amino acid sequence of normal haemoglobin to make it haemoglobin C?
Glutamic acid is changed to lysine.
2 )
Histidine is changed to leucine.
3 )
Leucine is changed to lysine.
4 )
Proline is changed to threonine.
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