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The diagram shows the cell cycle of a mammalian cell. 

Checkpoints in the cell cycle of mammals prevent the cycle from continuing when mistakes are made or DNA is damaged.

Four of the checkpoints are described.

1 Mitosis is blocked if DNA replication is incomplete.

2 Anaphase is blocked if the assembly of chromatids on the spindle is unsuccessful.

3 DNA replication is blocked if DNA is damaged.

4 DNA replication stops if damage to DNA has not been repaired.

In which phases of the cell cycle do these checkpoints occur?  

1 ) 

A

2 ) 

B

3 ) 

C

4 ) 

D

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