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What could occur as a result of inhaling the nicotine in tobacco smoke?

1 ) 

cilia lining the respiratory tract are paralysed, causing an increase in the secretion of mucus from enlarged goblet cells

2 ) 

diffusion into blood capillaries followed by the release of adrenaline, which increases blood pressure and heart rate

3 ) 

diffusion into the epithelial cells of the respiratory tract, increasing the risk of mutation and acting as a potential carcinogen

4 ) 

dissolves in the lining of the alveoli, causing a breakdown in the alveolar walls and a decrease in surface area for gas exchange

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