Which statements about the Michaelis–Menten constant ($K_{m}$) are correct?
1. The higher the $K_{m}$, the higher the enzyme affinity for the substrate.
2. $K_{m}$ is a measure of the degree of enzyme affinity for the substrate.
3. $K_{m}$ is defined as the substrate concentration at which the enzyme functions at half its maximum rate.
1 )
1, 2 and 3
2 )
1 and 2 only
3 )
1 and 3 only
2 and 3 only
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